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Autism spectrum disorder (ASD) is a common neurological disorder.Although the etiologies of ASD have been widely speculated, evidence also supports the pathogenic role of cutaneous inflammation in autism.The prevalence of ASD is higher in individuals with inflammatory dermatoses than in those without inflammatory diseases.Anti-inflammation therapy

Switch-like responses arising from bistability have been linked to cell signaling processes and memory.Revealing the shape and properties of the set of parameters that lead to bistability is necessary to understand the underlying biological mechanisms, but is a complex mathematical problem.We present an efficient approach to address a basic topolog

Duplication of centrosomes once per cell cycle is essential for bipolar spindle formation and genome maintenance and is controlled in part by cyclin-dependent kinases (Cdks).Our study identifies Sfi1, a conserved component of centrosomes, as the first Cdk substrate required to restrict centrosome duplication to once per cell cycle.We found that red